Future Products

Selected compounds currently prioritized for development at Biolinks. Contact us for early access, availability timing, or bulk interest.

For Research Use Only. Not for human or veterinary use.

Nafuredin-γ

Product ID: 1
Nafuredin-γ chemical structure
Mechanism
γ-lactone form of nafuredin
Primary Target
Complex I
Pathway
Electron transport chain
Chemical Class
Fungal polyketide
Summary helminth complex I inhibitor; NADH-fumarate reductase inhibitor; anthelmintic natural product; fungal metabolite; mitochondrial inhibitor
Details
Nafuredin-γ is a gamma-lactone form of nafuredin with inhibitory activity against helminth mitochondrial complex I
Basic Data MW: 360.49 / UN: -20°C
Source Organism Aspergillus niger FT-0554
Discovery Year 2005
Keywords
mitochondrial complex i inhibitor
References
  1. Shiomi et al. 2005
    DOI: Shiomi K et al., J Antibiot. 2005
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Bottromycin A2 (CAS: 15005-62-6)

Product ID: 2
Bottromycin A2 chemical structure
Mechanism
RiPP antibiotic active against resistant bacteria
Primary Target
Bacterial ribosome
Pathway
Protein synthesis
Chemical Class
RiPP peptide antibiotic
Summary bottromycin; RiPP; antibacterial natural product; MRSA active; VRE active; translation inhibitor; ribosome-targeting antibiotic
Details
Bottromycin A2 is a structurally unique RiPP antibiotic active against Gram-positive pathogens including resistant strains
Basic Data MW: 823.1 / UN: -20°C
Source Organism Streptomyces bottropensis
Discovery Year 1957
Keywords
ribosomal peptide antibiotic translation inhibitor
References
  1. Shimamura et al. 2009
    DOI: Shimamura H et al., Angew Chem Int Ed. 2009
  2. 10.1002/anie.200804138
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Efrotomycin (CAS: 56592-32-6)

Product ID: 3
Efrotomycin chemical structure
Mechanism
Elfamycin antibiotic targeting EF-Tu
Primary Target
EF-Tu
Pathway
Protein synthesis
Chemical Class
Glycosylated polyketide antibiotic
Summary efrotomycin; elfamycin; EF-Tu inhibitor; translation inhibitor; polyketide antibiotic
Details
Efrotomycin is an elfamycin antibiotic that inhibits bacterial protein synthesis via EF-Tu binding
Basic Data MF: C59H88N2O20 / MW: 1145.3 / UN: -20°C
Source Organism Nocardia lactamdurans
Discovery Year 1985
Keywords
ef-tu inhibitor protein synthesis inhibitor
References
  1. Dewey et al. 1985
    DOI: Dewey RS et al., J Antibiot. 1985
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