Cycloaspeptide A is a fungal cyclic peptide used as a nonribosomal peptide scaffold.
Details
Cycloaspeptide A is a nonribosomal cyclic peptide originally isolated from Penicillium species, including psychrotolerant and endophytic strains. Its structure was elucidated by NMR, MS, and X-ray crystallography in studies describing related cycloaspeptides. Although it exhibits low cytotoxicity and limited antibacterial activity, cycloaspeptide A represents a characteristic fungal NRPS-derived scaffold found in diverse ecological niches. It is primarily used as a chemical ecology and secondary metabolite research reference compound.