Name: Dihydrochlamydocin
Brand: Biolinks K.K.
SKU: BLK-0820

For Research Use Only. Not for human or veterinary use.

Dihydrochlamydocin (CAS: 157618-75-2) Product ID: BLK-0820 CAS 157618-75-2 Mechanism HDAC inhibitor Primary Target Histone deacetylases (HDACs) Pathway Epigenetic regulation; Chromatin acetylation
Structure
CAS	157618-75-2
Molecular Formula	C28H40N4O6
Molecular Weight	528.65
Price	1mg: USD 190.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95% [View LC/UV Data]
NMR Data	1H NMR (CDCl3, 500 MHz) [View]
Source Organism	Verticillium sp.
Summary	Dihydrochlamydocin is a cyclic tetrapeptide that inhibits histone deacetylases (HDACs).
Details	Dihydrochlamydocin is a cyclic tetrapeptide fungal metabolite structurally related to chlamydocin and HC-toxin. Conformational studies reveal a constrained bis-β-turn backbone that supports its bioactive configuration. It acts as a histone deacetylase (HDAC) inhibitor, modulating chromatin acetylation and affecting transcriptional regulation. Due to its epigenetic activity, dihydrochlamydocin is used as a chemical probe in studies of chromatin biology and cancer-related gene expression.
Browse Related	Mechanism HDAC inhibitor Open full index Primary Target Histone deacetylases (HDACs) Open full index Pathway Epigenetic regulation; Chromatin acetylation Open full index Chemical Class Cyclic tetrapeptide Open full index
Mechanism	HDAC inhibitor
Primary Target	Histone deacetylases (HDACs)
Pathway	Epigenetic regulation; Chromatin acetylation
Chemical Class	Cyclic tetrapeptide
Discovery Year	1983
Keywords	histone deacetylase inhibitor hdac inhibitor epigenetic modulator chromatin regulator cyclic tetrapeptide natural product fungal metabolite epigenetics research tool
References	Mastropaolo et al., Biochem Biophys Res Commun, 1983 DOI: 10.1016/0006-291X(83)90424-2
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Documents 📄 Safety Data Sheet (SDS) – Download PDF 📄 Product Specification Sheet (PDS) – Download PDF 🧪 Certificate of Manufacture (CofM) – Download HTML
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Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.
Representative NMR Data 1H NMR (CDCl3, 500 MHz) Representative spectral data. Actual batch data may vary.

Dihydrochlamydocin (CAS: 157618-75-2)